/* GLOBAL VARIABLES */
  :root {
    --page-primary: #3498db;
    --page-secondary: #2c3e50;
    --page-accent: #e74c3c;
    --page-bg: #f5f7fa;
    --page-card: #ffffff;
    --page-text: #4a5568;
    --page-heading: #2d3748;
    --page-border: #e2e8f0;
    --page-light-bg: #f7fbfe;
    --page-note-bg: #fef9e7;
    --page-note-border: #fcefc0;
    --page-gradient: linear-gradient(135deg, #667eea 0%, #764ba2 100%);
    --page-shadow-sm: 0 2px 4px rgba(0,0,0,0.06);
    --page-shadow-md: 0 4px 12px rgba(0,0,0,0.08);
    --page-shadow-lg: 0 10px 25px rgba(0,0,0,0.1);
    --page-shadow-xl: 0 20px 40px rgba(0,0,0,0.15);
    
    /* Mobile-first spacing */
    --section-spacing: 20px;
    --content-padding: 10px;
    --hero-padding-mobile: 30px 0 20px;
    --card-radius: 0px;
  }

  /* Hero Section - COMPACT MOBILE */
  .page-hero {
    background: linear-gradient(135deg, #2c3e50 0%, #34495e 100%);
    padding: var(--hero-padding-mobile);
    position: relative;
    overflow: hidden;
  }

  .page-hero::before {
    content: '';
    position: absolute;
    top: 0;
    left: 0;
    right: 0;
    bottom: 0;
    background: url("data:image/svg+xml,%3Csvg width='60' height='60' viewBox='0 0 60 60' xmlns='http://www.w3.org/2000/svg'%3E%3Cg fill='none' fill-rule='evenodd'%3E%3Cg fill='%23ffffff' fill-opacity='0.03'%3E%3Cpath d='M36 34v-4h-2v4h-4v2h4v4h2v-4h4v-2h-4zm0-30V0h-2v4h-4v2h4v4h2V6h4V4h-4zM6 34v-4H4v4H0v2h4v4h2v-4h4v-2H6zM6 4V0H4v4H0v2h4v4h2V6h4V4H6z'/%3E%3C/g%3E%3C/g%3E%3C/svg%3E");
    opacity: 0.5;
  }

  .page-hero-content {
    max-width: 900px;
    margin: 0 auto;
    padding: 0 15px;
    position: relative;
    z-index: 1;
  }

  .page-title {
    font-size: 1.5rem;
    color: #ffffff;
    margin: 0;
    font-weight: 700;
    line-height: 1.2;
    text-shadow: 0 2px 10px rgba(0,0,0,0.2);
    text-align: center;
  }

  /* Main Layout - EDGE-TO-EDGE ON MOBILE */
  .page-layout {
    max-width: 1400px;
    margin: -10px auto 20px;
    display: block;
    padding: 0;
    position: relative;
    z-index: 2;
  }

  /* Table of Contents - HIDDEN ON MOBILE */
  .toc-container {
    display: none;
  }

  /* Main Content Area - EDGE-TO-EDGE ON MOBILE */
  .page-content {
    background: var(--page-card);
    border-radius: var(--card-radius);
    padding: var(--content-padding);
    box-shadow: none;
    border: none;
    max-width: 100%;
    position: relative;
    overflow-x: hidden;
    overflow-y: visible;
  }

  /* Animated color line at top of content */
  .page-content::before {
    content: '';
    position: absolute;
    top: 0;
    left: 0;
    right: 0;
    height: 4px;
    background: linear-gradient(90deg, var(--page-accent) 0%, var(--page-primary) 50%, var(--page-accent) 100%);
    background-size: 200% 100%;
    animation: shimmer 3s linear infinite;
    border-radius: var(--card-radius) var(--card-radius) 0 0;
    z-index: 10;
  }

  /* Hide duplicate h1 title in content */
  .page-content > h1:first-child {
    display: none;
  }

  /* Content Typography - COMPACT MOBILE */
  .page-content h2 {
    color: var(--page-secondary);
    font-size: 1.3rem;
    margin: 20px 0 12px;
    padding-bottom: 8px;
    border-bottom: 2px solid var(--page-border);
    position: relative;
    font-weight: 600;
    display: flex;
    align-items: center;
    flex-wrap: wrap;
  }

  .page-content h2::after {
    content: '';
    position: absolute;
    bottom: -2px;
    left: 0;
    width: 30px;
    height: 3px;
    background: var(--page-accent);
    border-radius: 2px;
  }

  .page-content h2 i {
    margin-right: 8px;
    color: var(--page-accent);
  }

  .page-content h3 {
    color: var(--page-heading);
    font-size: 1.1rem;
    margin: 18px 0 10px;
    font-weight: 600;
    display: flex;
    align-items: center;
    flex-wrap: wrap;
  }

  .page-content h3 i {
    margin-right: 8px;
    color: var(--page-accent);
  }

  .page-content p {
    line-height: 1.6;
    margin-bottom: 12px;
    color: var(--page-text);
    font-size: 0.95rem;
  }

  .page-content ul,
  .page-content ol {
    margin: 12px 0;
    padding-left: 20px;
  }

  .page-content li {
    margin-bottom: 8px;
    line-height: 1.6;
    color: var(--page-text);
    font-size: 0.95rem;
  }

  .page-content a {
    color: var(--page-primary);
    text-decoration: none;
    border-bottom: 2px solid transparent;
    transition: all 0.3s ease;
    font-weight: 500;
  }

  .page-content a:hover {
    color: var(--page-accent);
    border-bottom-color: var(--page-accent);
  }

  /* Protocol Cards - COMPACT */
  .protocol-summary {
    display: grid;
    grid-template-columns: 1fr;
    gap: 12px;
    margin: 15px 0;
  }

  .protocol-card {
    background: linear-gradient(135deg, var(--page-light-bg) 0%, #ffffff 100%);
    border-radius: var(--card-radius);
    padding: 15px;
    box-shadow: var(--page-shadow-sm);
    transition: all 0.3s ease;
    border-left: 4px solid var(--page-accent);
  }

  .protocol-card:hover {
    transform: translateY(-2px);
    box-shadow: var(--page-shadow-md);
  }

  /* Intro Card - COMPACT MOBILE */
  .intro-card {
    background: linear-gradient(135deg, #f8fbff 0%, #ffffff 100%);
    border-radius: var(--card-radius);
    padding: 15px;
    box-shadow: var(--page-shadow-sm);
    display: flex;
    flex-direction: column;
    align-items: center;
    gap: 15px;
    margin-bottom: 20px;
    border: 1px solid var(--page-border);
    text-align: center;
  }

  .intro-content {
    flex: 1;
    width: 100%;
  }

  .intro-content h2 {
    text-align: left;
    margin-top: 0;
  }

  .intro-content ul {
    text-align: left;
  }

  .intro-image img {
    max-width: 180px;
    width: 100%;
    border-radius: 6px;
  }

  /* Section Blocks - COMPACT */
  .section-block {
    background: linear-gradient(135deg, var(--page-light-bg) 0%, #ffffff 100%);
    border-radius: var(--card-radius);
    padding: var(--content-padding);
    margin-bottom: var(--section-spacing);
    box-shadow: var(--page-shadow-sm);
    border: 1px solid var(--page-border);
  }

  /* Tables - OPTIMIZED */
  .table-responsive {
    width: 100%;
    overflow-x: auto;
    -webkit-overflow-scrolling: touch;
    margin: 15px 0;
  }

  .page-content table {
    width: 100%;
    min-width: 450px;
    border-collapse: separate;
    border-spacing: 0;
    margin: 0;
    border-radius: var(--card-radius);
    overflow: hidden;
    box-shadow: var(--page-shadow-sm);
  }

  .page-content th {
    background: linear-gradient(135deg, var(--page-primary), #5ba3e0);
    color: white;
    padding: 10px;
    text-align: left;
    font-weight: 600;
    text-transform: uppercase;
    font-size: 0.8rem;
    letter-spacing: 0.5px;
  }

  .page-content td {
    padding: 10px;
    border-bottom: 1px solid var(--page-border);
    background: var(--page-card);
    font-size: 0.9rem;
  }

  .page-content tr:hover td {
    background: #f8fbff;
  }

  .page-content tr:last-child td {
    border-bottom: none;
  }

  /* IMPROVED Dosing & Reconstitution Wrapper */
  .dosing-recon-wrapper {
    margin: var(--section-spacing) 0;
    padding: 0;
    background: transparent;
  }

  .dosing-recon-wrapper .dr-container {
    max-width: 100%;
    margin: 0;
    background: linear-gradient(135deg, #f8fbff 0%, #ffffff 100%);
    border-radius: var(--card-radius);
    overflow: hidden;
    box-shadow: var(--page-shadow-md);
    border: 1px solid var(--page-border);
  }

  .dosing-recon-wrapper header {
    padding: 20px 15px;
    background: linear-gradient(135deg, var(--page-primary), #5ba3e0);
    color: #fff;
    position: relative;
    overflow: hidden;
  }

  .dosing-recon-wrapper header::before {
    content: '';
    position: absolute;
    top: 0;
    left: 0;
    right: 0;
    bottom: 0;
    background: url("data:image/svg+xml,%3Csvg width='40' height='40' viewBox='0 0 40 40' xmlns='http://www.w3.org/2000/svg'%3E%3Cg fill='%23ffffff' fill-opacity='0.05'%3E%3Cpath d='M20 20L0 0v20h20zm0 0l20 20V20H20zm0 0L0 40h20V20zm0 0l20-20H20v20z'/%3E%3C/g%3E%3C/svg%3E");
    opacity: 0.3;
  }

  .dosing-recon-wrapper header > div {
    position: relative;
    z-index: 1;
  }

  .dosing-recon-wrapper header h2 {
    font-size: 1.3rem;
    margin: 0;
    color: #fff;
    border: none !important;
    padding: 0 !important;
    font-weight: 600;
    display: flex;
    align-items: center;
    gap: 10px;
  }

  .dosing-recon-wrapper header h2 i {
    font-size: 1.2rem;
  }

  .dosing-recon-wrapper header h2::after {
    display: none;
  }

  .dosing-recon-wrapper header p {
    font-size: 0.9rem;
    margin: 8px 0 0 0;
    opacity: 0.95;
    color: #e8f4ff;
    font-weight: 400;
    letter-spacing: 0.3px;
  }

  .dosing-recon-wrapper section {
    padding: 20px 15px;
    border-bottom: 1px solid var(--page-border);
    background: #fff;
  }
  
  .dosing-recon-wrapper section:last-of-type {
    border-bottom: none;
  }

  .dosing-recon-wrapper section h2 {
    font-size: 1.15rem;
    margin-bottom: 15px;
    color: var(--page-secondary);
    border-left: 4px solid var(--page-accent);
    padding-left: 12px;
    border-bottom: none;
    font-weight: 600;
  }

  .dosing-recon-wrapper section h2::after {
    display: none;
  }

  /* Improved table styling for mobile */
  .dosing-recon-wrapper .table-responsive {
    margin: 15px -5px;
    padding: 0;
    overflow-x: auto;
    -webkit-overflow-scrolling: touch;
  }

  .dosing-recon-wrapper table {
    width: 100%;
    min-width: auto;
    border-collapse: separate;
    border-spacing: 0;
    margin: 0;
    border-radius: 8px;
    overflow: hidden;
    box-shadow: 0 2px 8px rgba(0,0,0,0.08);
    background: #fff;
  }

  .dosing-recon-wrapper th {
    background: linear-gradient(135deg, #4a90e2, #5ba3e0);
    color: white;
    padding: 12px 10px;
    text-align: left;
    font-weight: 600;
    text-transform: uppercase;
    font-size: 0.75rem;
    letter-spacing: 0.5px;
    white-space: nowrap;
  }

  .dosing-recon-wrapper td {
    padding: 12px 10px;
    border-bottom: 1px solid #f0f0f0;
    background: #fff;
    font-size: 0.9rem;
    color: var(--page-text);
  }

  .dosing-recon-wrapper tr:last-child td {
    border-bottom: none;
  }

  .dosing-recon-wrapper tr:hover td {
    background: #f8fbff;
  }

  /* Make first column slightly narrower on mobile */
  .dosing-recon-wrapper td:first-child,
  .dosing-recon-wrapper th:first-child {
    width: 30%;
  }

  .dosing-recon-wrapper section p {
    font-size: 0.9rem;
    line-height: 1.6;
    color: var(--page-text);
    margin-bottom: 15px;
  }

  .dosing-recon-wrapper section ol {
    margin: 15px 0;
    padding-left: 20px;
  }

  .dosing-recon-wrapper section ol li {
    margin-bottom: 10px;
    font-size: 0.9rem;
    line-height: 1.5;
    color: var(--page-text);
  }

  .dosing-recon-wrapper footer {
    padding: 15px;
    background: linear-gradient(135deg, #fef9e7, #fdf6e3);
    border-top: 2px solid #fcefc0;
    text-align: center;
    font-style: italic;
    color: #7a6736;
    font-size: 0.85rem;
  }

  .dosing-recon-wrapper footer p {
    margin: 0;
  }

  /* Image Gallery - COMPACT 2 COLUMNS */
  .image-gallery {
    display: grid;
    grid-template-columns: repeat(2, 1fr);
    gap: 10px;
    margin: 15px 0;
  }

  .product-card {
    display: flex;
    flex-direction: column;
    align-items: center;
    justify-content: space-between;
    padding: 12px;
    border-radius: var(--card-radius);
    background: #fff;
    box-shadow: var(--page-shadow-sm);
    transition: all 0.3s ease;
    border: 1px solid var(--page-border);
    min-height: 180px;
  }

  .product-card:hover {
    transform: translateY(-2px);
    box-shadow: var(--page-shadow-md);
  }

  .product-card img {
    width: 100%;
    max-width: 100px;
    height: 100px;
    object-fit: cover;
    border-radius: 6px;
    margin-bottom: 10px;
  }

  .product-card a {
    display: inline-block;
    background: linear-gradient(135deg, var(--page-accent), #c0392b);
    color: #fff !important;
    font-weight: 600;
    padding: 6px 12px;
    border-radius: 5px;
    text-decoration: none !important;
    transition: all 0.3s ease;
    border: none !important;
    font-size: 0.8rem;
    text-align: center;
    width: 100%;
    max-width: 120px;
  }

  .product-card a:hover {
    transform: translateY(-1px);
    box-shadow: 0 3px 10px rgba(231, 76, 60, 0.3);
  }

  /* Important Note - COMPACT */
  .important-note {
    background: var(--page-note-bg);
    border: 2px solid var(--page-note-border);
    border-radius: var(--card-radius);
    padding: 15px;
    margin: var(--section-spacing) 0;
    color: #7a6736;
  }
  
  .important-note h3 {
    margin-top: 0;
    margin-bottom: 8px;
    color: #7a6736;
    font-size: 1rem;
  }
  
  .important-note p {
    margin: 0;
    font-size: 0.9rem;
  }

  /* Supplier Info - COMPACT */
  .supplier-info {
    background: linear-gradient(135deg, #e8f4f8 0%, #ffffff 100%);
    border-radius: var(--card-radius);
    padding: 15px;
    margin: var(--section-spacing) 0;
    box-shadow: var(--page-shadow-sm);
    border-left: 5px solid var(--page-accent);
  }

  /* References Section - STREAMLINED */
  .references-section {
    margin-top: var(--section-spacing);
    padding: 0;
    background: transparent;
  }
  
  .references-section h2 {
    margin-bottom: 15px;
    padding-bottom: 10px;
    border-bottom: 3px solid var(--page-accent);
  }

  .reference-list {
    list-style: none;
    padding: 0;
    margin: 0;
  }

  .reference-list li {
    margin-bottom: 12px;
    padding: 12px;
    background: linear-gradient(135deg, #f8fbff 0%, #ffffff 100%);
    border-radius: var(--card-radius);
    border-left: 3px solid var(--page-primary);
    box-shadow: var(--page-shadow-sm);
    transition: all 0.3s ease;
  }

  .reference-list li:hover {
    transform: translateX(2px);
    box-shadow: var(--page-shadow-md);
  }

  .ref-line {
    display: flex;
    align-items: flex-start;
    margin-bottom: 8px;
    color: var(--page-heading);
    flex-wrap: wrap;
    font-size: 0.9rem;
  }

  .ref-line i {
    color: var(--page-accent);
    margin-right: 8px;
    margin-top: 2px;
    font-size: 0.8rem;
  }

  .ref-line strong {
    color: var(--page-secondary);
    font-weight: 600;
    margin-right: 5px;
  }

  .view-source {
    display: inline-flex;
    align-items: center;
    gap: 5px;
    padding: 5px 12px;
    background: linear-gradient(135deg, var(--page-accent), #c0392b);
    color: white !important;
    border-radius: 15px;
    text-decoration: none !important;
    transition: all 0.3s ease;
    font-size: 0.8rem;
    font-weight: 500;
    border: none !important;
  }

  .view-source:hover {
    transform: translateY(-1px);
    box-shadow: 0 3px 10px rgba(231, 76, 60, 0.3);
  }

  /* Animations */
  @keyframes fadeIn {
    from { opacity: 0; }
    to { opacity: 1; }
  }

  @keyframes fadeInUp {
    from {
      opacity: 0;
      transform: translateY(20px);
    }
    to {
      opacity: 1;
      transform: translateY(0);
    }
  }

  @keyframes shimmer {
    0% { background-position: -200% 0; }
    100% { background-position: 200% 0; }
  }

  /* Animation classes */
  .fade-in { animation: fadeIn 0.8s ease-out forwards; }
  .fadeUp { animation: fadeInUp 0.8s ease-out forwards; }
  .delay-1 { animation-delay: 0.1s; }
  .delay-2 { animation-delay: 0.2s; }
  .delay-3 { animation-delay: 0.3s; }
  .delay-4 { animation-delay: 0.4s; }

  /* TABLET STYLES */
  @media (min-width: 768px) {
    :root {
      --section-spacing: 25px;
      --content-padding: 25px;
      --hero-padding-mobile: 50px 0 35px;
      --card-radius: 10px;
    }
    
    .page-hero {
      padding: var(--hero-padding-mobile);
    }
    
    .page-title {
      font-size: 2rem;
    }
    
    .page-layout {
      margin: -20px auto 40px;
      padding: 0 20px;
    }
    
    .page-content {
      padding: var(--content-padding);
      border-radius: var(--card-radius);
      box-shadow: var(--page-shadow-md);
      border: 1px solid var(--page-border);
    }
    
    .page-content h2 {
      font-size: 1.5rem;
      margin: 30px 0 15px;
    }
    
    .page-content h3 {
      font-size: 1.2rem;
    }
    
    .page-content p {
      font-size: 1rem;
      margin-bottom: 15px;
    }
    
    .intro-card {
      flex-direction: row;
      text-align: left;
      padding: 20px;
      gap: 20px;
    }
    
    .intro-image img {
      max-width: 200px;
    }
    
    .protocol-card,
    .section-block {
      padding: 20px;
    }
    
    .image-gallery {
      grid-template-columns: repeat(3, 1fr);
      gap: 15px;
    }
    
    .product-card {
      padding: 15px;
      min-height: 200px;
    }
    
    .product-card img {
      max-width: 120px;
      height: 120px;
    }
    
    .product-card a {
      padding: 8px 16px;
      font-size: 0.85rem;
    }
    
    .dosing-recon-wrapper header {
      padding: 25px;
    }
    
    .dosing-recon-wrapper header h2 {
      font-size: 1.5rem;
    }
    
    .dosing-recon-wrapper header h2 i {
      font-size: 1.4rem;
    }
    
    .dosing-recon-wrapper header p {
      font-size: 1rem;
      margin-top: 10px;
    }
    
    .dosing-recon-wrapper section {
      padding: 25px;
    }
    
    .dosing-recon-wrapper section h2 {
      font-size: 1.3rem;
      margin-bottom: 20px;
    }
    
    .dosing-recon-wrapper table {
      min-width: 100%;
    }
    
    .dosing-recon-wrapper th {
      padding: 14px 15px;
      font-size: 0.85rem;
    }
    
    .dosing-recon-wrapper td {
      padding: 14px 15px;
      font-size: 0.95rem;
    }
    
    .dosing-recon-wrapper section p {
      font-size: 0.95rem;
    }
    
    .dosing-recon-wrapper section ol li {
      font-size: 0.95rem;
    }
    
    .dosing-recon-wrapper footer {
      padding: 20px;
      font-size: 0.9rem;
    }
    
    .reference-list li {
      padding: 15px;
    }
  }

  /* DESKTOP STYLES */
  @media (min-width: 1024px) {
    :root {
      --section-spacing: 35px;
      --content-padding: 35px;
      --hero-padding-mobile: 70px 0 50px;
      --card-radius: 12px;
    }
    
    .page-hero {
      padding: var(--hero-padding-mobile);
    }
    
    .page-title {
      font-size: 2.5rem;
      margin-bottom: 10px;
    }
    
    .page-layout {
      margin: -30px auto 50px;
      display: flex;
      gap: 35px;
      padding: 0 20px;
    }
    
    /* Show TOC on desktop */
    .toc-container {
      display: block;
      width: 280px;
      background: var(--page-card);
      border-radius: var(--card-radius);
      padding: 25px;
      position: sticky;
      top: 90px;
      height: fit-content;
      box-shadow: var(--page-shadow-lg);
      border: 1px solid var(--page-border);
      transition: all 0.3s ease;
    }
    
    .toc-title {
      font-size: 1.2rem;
      color: var(--page-secondary);
      margin-bottom: 18px;
      font-weight: 600;
      padding-bottom: 12px;
      border-bottom: 3px solid var(--page-accent);
      display: flex;
      align-items: center;
      gap: 8px;
    }
    
    .toc-title i {
      color: var(--page-accent);
      font-size: 1rem;
    }
    
    .nav-list {
      list-style: none;
      padding: 0;
      margin: 0;
    }
    
    .nav-list li {
      margin-bottom: 3px;
    }
    
    .nav-list a {
      display: flex;
      align-items: center;
      color: var(--page-text);
      font-size: 0.9rem;
      padding: 8px 12px;
      border-radius: 8px;
      transition: all 0.3s ease;
      text-decoration: none;
      position: relative;
      overflow: hidden;
    }
    
    .nav-list a::before {
      content: '';
      position: absolute;
      left: 0;
      top: 0;
      height: 100%;
      width: 3px;
      background: var(--page-accent);
      transform: translateX(-100%);
      transition: transform 0.3s ease;
    }
    
    .nav-list a:hover {
      background: linear-gradient(90deg, rgba(231,76,60,0.1) 0%, transparent 100%);
      color: var(--page-accent);
      padding-left: 18px;
    }
    
    .nav-list a:hover::before {
      transform: translateX(0);
    }
    
    .nav-list a.active {
      background: linear-gradient(90deg, rgba(52,152,219,0.1) 0%, transparent 100%);
      color: var(--page-primary);
      font-weight: 600;
    }
    
    .nav-list a i {
      margin-right: 8px;
      width: 18px;
      text-align: center;
      font-size: 0.8rem;
      opacity: 0.7;
    }
    
    .page-content {
      flex: 1;
      max-width: 900px;
      padding: var(--content-padding);
      border-radius: var(--card-radius);
    }
    
    /* Center content when TOC sidebar is absent (contact, login, register) */
    .page-content:only-child {
      margin: 0 auto;
    }
    
    .page-content h2 {
      font-size: 1.7rem;
      margin: 35px 0 18px;
    }
    
    .page-content h3 {
      font-size: 1.3rem;
      margin: 25px 0 12px;
    }
    
    .page-content p {
      font-size: 1.02rem;
      margin-bottom: 18px;
      line-height: 1.7;
    }
    
    .page-content ul,
    .page-content ol {
      margin: 18px 0;
      padding-left: 28px;
    }
    
    .page-content li {
      margin-bottom: 10px;
      line-height: 1.7;
    }
    
    .intro-card {
      padding: 30px;
      gap: 30px;
      margin-bottom: 30px;
    }
    
    .intro-image img {
      max-width: 220px;
    }
    
    .protocol-card {
      padding: 22px;
    }
    
    .section-block {
      padding: 30px;
      margin-bottom: 30px;
    }
    
    .page-content table {
      margin: 25px 0;
    }
    
    .page-content th,
    .page-content td {
      padding: 12px;
    }
    
    .dosing-recon-wrapper header {
      padding: 30px;
    }
    
    .dosing-recon-wrapper header h2 {
      font-size: 1.7rem;
    }
    
    .dosing-recon-wrapper header h2 i {
      font-size: 1.5rem;
    }
    
    .dosing-recon-wrapper header p {
      font-size: 1.05rem;
    }
    
    .dosing-recon-wrapper section {
      padding: 30px;
    }
    
    .dosing-recon-wrapper section h2 {
      font-size: 1.4rem;
      padding-left: 15px;
    }
    
    .dosing-recon-wrapper th {
      padding: 15px 20px;
      font-size: 0.9rem;
    }
    
    .dosing-recon-wrapper td {
      padding: 15px 20px;
      font-size: 1rem;
    }
    
    .dosing-recon-wrapper section p {
      font-size: 1rem;
      margin-bottom: 18px;
    }
    
    .dosing-recon-wrapper section ol li {
      font-size: 1rem;
      margin-bottom: 12px;
    }
    
    .dosing-recon-wrapper footer {
      padding: 25px;
      font-size: 0.95rem;
    }
    
    .image-gallery {
      grid-template-columns: repeat(4, 1fr);
      margin: 25px 0;
    }
    
    .product-card {
      padding: 18px;
    }
    
    .product-card img {
      width: 130px;
      height: 130px;
    }
    
    .product-card a {
      padding: 8px 18px;
      font-size: 0.9rem;
    }
    
    .reference-list li {
      padding: 18px;
      margin-bottom: 15px;
    }
    
    .ref-line {
      font-size: 0.95rem;
    }
    
    .view-source {
      padding: 6px 14px;
      font-size: 0.85rem;
    }
  }

  /* LARGE DESKTOP */
  @media (min-width: 1440px) {
    .page-title {
      font-size: 3rem;
    }
    
    .toc-container {
      width: 300px;
      padding: 30px;
    }
    
    .page-content {
      padding: 40px;
    }
  }

  .pdc-wrap{--pc:#3498db;--sc:#2c3e50;--ac:#e74c3c;--ok:#27ae60;--warn:#e67e22;--ink:#43586b;--mut:#5a6b7b;--line:#e3e8ee;font-family:'Poppins',system-ui,sans-serif;color:var(--sc);max-width:1080px;margin:0 auto;}
  .pdc-wrap *:focus-visible{outline:2px solid var(--pc);outline-offset:2px;border-radius:4px;}
  .pdc-intro{font-size:1.02rem;line-height:1.65;color:var(--ink);margin:0 0 26px;}

  /* ── Layout ── */
  .pdc-grid{display:grid;grid-template-columns:1fr 1fr;gap:22px;align-items:stretch;}
  @media(max-width:820px){.pdc-grid{grid-template-columns:1fr;}}
  .pdc-card{border:1px solid var(--line);border-radius:16px;padding:24px 24px 26px;background:linear-gradient(180deg,#f8fbff 0%,#fff 60%);box-shadow:0 1px 3px rgba(16,42,67,.05);}
  .pdc-card h2{font-size:1.25rem;margin:0 0 4px;color:var(--sc);display:flex;align-items:center;gap:10px;}
  .pdc-card h2 i{color:var(--pc);}
  .pdc-step{flex:0 0 auto;width:26px;height:26px;border-radius:50%;background:var(--pc);color:#fff;font-size:.85rem;font-weight:700;display:inline-flex;align-items:center;justify-content:center;}
  .pdc-card .pdc-hint{margin:0 0 18px;color:var(--mut);font-size:.9rem;line-height:1.45;}

  /* ── Fields ── */
  .pdc-field{margin:0 0 15px;}
  .pdc-field label{display:flex;align-items:center;gap:6px;font-weight:600;font-size:.9rem;margin:0 0 6px;color:#33485c;}
  .pdc-input{display:flex;border:1px solid #cfd8e3;border-radius:10px;overflow:hidden;background:#fff;transition:border-color .15s,box-shadow .15s;}
  .pdc-input:focus-within{border-color:var(--pc);box-shadow:0 0 0 3px rgba(52,152,219,.14);}
  .pdc-input input,.pdc-input select{border:0;padding:11px 13px;font-size:1rem;font-family:inherit;width:100%;min-width:0;outline:none;background:transparent;color:var(--sc);}
  .pdc-input .pdc-unit{flex:0 0 auto;background:#eef3f8;color:#52677b;font-size:.85rem;display:flex;align-items:center;padding:0 13px;border-left:1px solid #cfd8e3;font-weight:600;}
  .pdc-input select{cursor:pointer;}
  .pdc-chips{display:flex;flex-wrap:wrap;gap:6px;margin-top:7px;}
  .pdc-chips button{font-family:inherit;font-size:.76rem;font-weight:600;color:var(--mut);background:#fff;border:1px solid #dbe4ec;border-radius:999px;padding:3px 11px;cursor:pointer;transition:.12s;}
  .pdc-chips button:hover{color:var(--pc);border-color:var(--pc);background:#f2f9ff;}

  /* ── Tooltips ── */
  .pdc-tip{position:relative;display:inline-flex;}
  .pdc-tip-btn{position:relative;width:24px;height:24px;min-width:24px;min-height:24px;margin:-3.5px;border:0;background:transparent;color:#7d92a5;font-size:.68rem;font-weight:700;line-height:1;cursor:help;display:inline-flex;align-items:center;justify-content:center;padding:0;font-family:inherit;transition:.12s;}
  .pdc-tip-btn::before{content:'';position:absolute;inset:3.5px;border:1px solid #b9c8d6;border-radius:50%;background:#fff;}
  .pdc-tip-btn:hover,.pdc-tip-btn:focus-visible{color:var(--pc);}
  .pdc-tip-btn:hover::before,.pdc-tip-btn:focus-visible::before{border-color:var(--pc);}
  .pdc-tipbox{position:absolute;bottom:calc(100% + 9px);left:50%;transform:translateX(-50%) translateY(3px);width:max-content;max-width:min(250px,76vw);background:var(--sc);color:#eef4f9;font-size:.76rem;font-weight:400;line-height:1.5;padding:9px 11px;border-radius:9px;box-shadow:0 6px 18px rgba(16,42,67,.28);opacity:0;visibility:hidden;transition:opacity .15s,transform .15s;z-index:40;pointer-events:none;text-align:left;}
  .pdc-tipbox::after{content:'';position:absolute;top:100%;left:50%;transform:translateX(-50%);border:5px solid transparent;border-top-color:var(--sc);}
  .pdc-tip:hover .pdc-tipbox,.pdc-tip:focus-within .pdc-tipbox,.pdc-tip.open .pdc-tipbox{opacity:1;visibility:visible;transform:translateX(-50%) translateY(0);}
  .pdc-tip--edge .pdc-tipbox{left:auto;right:-8px;transform:translateY(3px);}
  .pdc-tip--edge .pdc-tipbox::after{left:auto;right:12px;transform:none;}
  .pdc-tip--edge:hover .pdc-tipbox,.pdc-tip--edge:focus-within .pdc-tipbox,.pdc-tip--edge.open .pdc-tipbox{transform:translateY(0);}
  .pdc-tip.suppressed .pdc-tipbox{opacity:0!important;visibility:hidden!important;pointer-events:none!important;}

  /* ── Step-1 outputs ── */
  .pdc-out{margin-top:20px;border-top:1px dashed #d6e0ea;padding-top:18px;}
  .pdc-out .pdc-row{display:flex;justify-content:space-between;align-items:baseline;gap:14px;padding:8px 0;border-bottom:1px solid #f0f4f8;}
  .pdc-out .pdc-row:last-child{border-bottom:0;}
  .pdc-out .pdc-row .k{color:#52677b;font-size:.92rem;display:inline-flex;align-items:center;gap:6px;}
  .pdc-out .pdc-row .v{font-weight:700;font-size:1.12rem;color:var(--sc);text-align:right;}
  .pdc-out .pdc-row .v.big{font-size:1.5rem;color:var(--pc);}

  /* ── Syringe size control ── */
  .pdc-seg{display:grid;grid-template-columns:repeat(3,1fr);gap:8px;}
  .pdc-seg button{font-family:inherit;border:1.5px solid #cfd8e3;background:#fff;border-radius:11px;padding:9px 6px 8px;cursor:pointer;text-align:center;transition:.14s;color:var(--sc);}
  .pdc-seg button .n{display:block;font-size:1.15rem;font-weight:700;line-height:1.1;}
  .pdc-seg button .s{display:block;font-size:.7rem;color:var(--mut);font-weight:600;margin-top:2px;}
  .pdc-seg button:hover{border-color:var(--pc);}
  .pdc-seg button[aria-pressed="true"]{border-color:var(--pc);background:linear-gradient(180deg,#eaf4fc,#f7fbff);box-shadow:0 0 0 3px rgba(52,152,219,.12);color:var(--pc);}
  .pdc-seg button[aria-pressed="true"] .s{color:var(--pc);}
  .pdc-seg-hint{margin:8px 0 0;font-size:.78rem;line-height:1.5;color:var(--mut);min-height:2.4em;}

  /* ── Results panel ── */
  .pdc-results{margin-top:22px;border:1px solid var(--line);border-radius:16px;background:linear-gradient(180deg,#fdfeff,#f6fafd);box-shadow:0 1px 3px rgba(16,42,67,.05);padding:24px 24px 22px;}
  .pdc-results h2{font-size:1.25rem;margin:0 0 14px;color:var(--sc);display:flex;align-items:center;gap:10px;}
  .pdc-results h2 i{color:var(--pc);}
  .pdc-validation{margin:16px 0 0;padding:12px 14px;border-left:4px solid #b42318;border-radius:0 8px 8px 0;background:#fff1f0;color:#7a271a;font-size:.9rem;font-weight:600;}
  .pdc-res-top{display:flex;flex-wrap:wrap;align-items:flex-end;gap:18px 34px;margin-bottom:6px;}
  .pdc-draw .lbl{display:flex;align-items:center;gap:6px;font-size:.82rem;font-weight:600;color:var(--mut);text-transform:uppercase;letter-spacing:.04em;}
  .pdc-draw .val{font-size:2.5rem;font-weight:700;color:var(--ac);line-height:1.05;}
  .pdc-draw .val small{font-size:1.05rem;font-weight:600;color:var(--mut);margin-left:6px;}
  .pdc-stats{display:flex;flex-wrap:wrap;gap:10px;}
  .pdc-stat{background:#fff;border:1px solid var(--line);border-radius:11px;padding:8px 14px;min-width:104px;}
  .pdc-stat .k{display:flex;align-items:center;gap:5px;font-size:.7rem;font-weight:600;color:var(--mut);text-transform:uppercase;letter-spacing:.04em;}
  .pdc-stat .v{font-size:1.06rem;font-weight:700;color:var(--sc);margin-top:1px;}
  @keyframes pdcPulse{0%{transform:scale(1)}35%{transform:scale(1.06)}100%{transform:scale(1)}}
  .pdc-pulse{animation:pdcPulse .3s ease;}

  /* ── Syringe ── */
  .pdc-syr{margin:14px 0 4px;}
  .pdc-syr svg{width:100%;height:auto;display:block;}
  .pdc-syr .barrel{fill:#fff;stroke:var(--sc);stroke-width:2.5;}
  .pdc-syr .barrel.over{stroke:var(--ac);}
  .pdc-syr .metal{fill:#b9c8d6;}
  .pdc-syr .tick{stroke:#93a7b8;stroke-width:1;}
  .pdc-syr .tick.major{stroke:var(--sc);stroke-width:1.6;}
  .pdc-syr .ticklbl{fill:#66798b;font-size:9.5px;font-weight:600;font-family:'Poppins',system-ui,sans-serif;}
  .pdc-syr .axis{fill:#8a99a8;font-size:9px;font-weight:600;letter-spacing:.06em;font-family:'Poppins',system-ui,sans-serif;}
  #pdLiquid{fill:url(#pdcLiq);transform-box:fill-box;transform-origin:left center;transform:scaleX(0);transition:transform .35s cubic-bezier(.22,.9,.35,1);}
  #pdSeal{transition:transform .35s cubic-bezier(.22,.9,.35,1);}
  #pdArrow{transition:transform .35s cubic-bezier(.22,.9,.35,1),opacity .2s;fill:var(--ac);}
  @media(prefers-reduced-motion:reduce){#pdLiquid,#pdSeal,#pdArrow,.pdc-tipbox{transition:none;}.pdc-pulse{animation:none;}}

  /* ── Guidance ── */
  .pdc-guide{margin-top:10px;display:flex;flex-direction:column;gap:6px;}
  .pdc-mark{font-size:.86rem;color:var(--ink);}
  .pdc-mark.ok{color:var(--ok);font-weight:600;}
  .pdc-mark.off{color:var(--warn);}
  .pdc-note{font-size:.84rem;line-height:1.55;color:var(--warn);margin:0;}
  .pdc-note.alert{color:var(--ac);font-weight:600;}
  .pdc-rec{display:none;margin-top:2px;}
  .pdc-rec button{font-family:inherit;font-size:.78rem;font-weight:600;color:var(--pc);background:#eef7ff;border:1px dashed var(--pc);border-radius:999px;padding:5px 13px;cursor:pointer;transition:.12s;}
  .pdc-rec button:hover{background:var(--pc);color:#fff;border-style:solid;}
  .pdc-res-foot{display:flex;justify-content:flex-end;margin-top:12px;}
  .pdc-copy{font-family:inherit;font-size:.82rem;font-weight:600;color:var(--pc);background:#fff;border:1px solid #d3e3f0;border-radius:9px;padding:8px 14px;cursor:pointer;transition:.12s;display:inline-flex;align-items:center;gap:7px;}
  .pdc-copy:hover{background:#eaf4fc;border-color:var(--pc);}
  .pdc-copy.done{color:var(--ok);border-color:var(--ok);}

  /* ── SEO article — inherits page.php .page-content typography; rules below are additive ── */
  .pdc-article{margin-top:34px;}
  .pdc-article .pdc-keybox{background:linear-gradient(135deg,#eaf4fc,#f7fbff);border:1px solid #cfe4f5;border-left:4px solid var(--pc);border-radius:12px;padding:16px 18px;margin:0 0 24px;font-size:1rem;line-height:1.65;color:var(--sc);}
  .pdc-article ol.pdc-steps{list-style:none;counter-reset:pdcstep;padding-left:0;margin:18px 0;display:grid;gap:12px;}
  .pdc-article ol.pdc-steps>li{counter-increment:pdcstep;position:relative;padding:14px 18px 14px 56px;background:#f8fbff;border:1px solid var(--line);border-radius:12px;font-size:.95rem;line-height:1.6;color:#43586b;margin:0;}
  .pdc-article ol.pdc-steps>li::before{content:counter(pdcstep);position:absolute;left:14px;top:13px;width:28px;height:28px;border-radius:50%;background:var(--pc);color:#fff;font-size:.9rem;font-weight:700;display:flex;align-items:center;justify-content:center;}
  .pdc-article .pdc-article-note{background:#fdf2f0;border-left:4px solid var(--ac);border-radius:0 10px 10px 0;padding:14px 16px;font-size:.88rem;line-height:1.55;color:#7d4a42;margin:28px 0 0;}
  .pdc-article ol.pdc-refs{padding-left:22px;margin:12px 0 0;}
  .pdc-article ol.pdc-refs>li{font-size:.82rem;line-height:1.55;color:#5a6b7b;margin-bottom:9px;}
  .pdc-article ol.pdc-refs>li a{color:var(--pc);word-break:break-word;}

  .pdc-disc{margin:30px 0 0;padding:16px 18px;border-left:4px solid var(--ac);background:#fdf2f0;border-radius:0 10px 10px 0;font-size:.86rem;color:#7d4a42;line-height:1.55;}
  .pdc-foot-links{margin-top:26px;display:flex;flex-wrap:wrap;gap:10px;}
  .pdc-foot-links a{text-decoration:none;font-weight:600;font-size:.9rem;color:var(--pc);border:1px solid #d3e3f0;border-radius:8px;padding:9px 14px;background:#fff;transition:.12s;}
  .pdc-foot-links a:hover{background:#eaf4fc;border-color:var(--pc);}

  @media(max-width:1024px){
    .pdc-input input,.pdc-input select,.pdc-chips button,.pdc-seg button,.pdc-rec button,.pdc-copy,.pdc-foot-links a{min-height:44px;}
    .pdc-chips button,.pdc-rec button{padding-top:8px;padding-bottom:8px;}
    .pdc-tip-btn{width:44px;height:44px;min-width:44px;min-height:44px;margin:-10px;}
    .pdc-tip-btn::before{inset:13.5px;}
    .pdc-foot-links a{display:inline-flex;align-items:center;}
  }

  @media(max-width:600px){
    .pdc-card,.pdc-results{padding:18px 16px;border-radius:14px;}
    .pdc-card h2,.pdc-results h2{font-size:1.15rem;}
    .pdc-out .pdc-row{display:grid;grid-template-columns:minmax(0,1fr) auto;align-items:center;gap:8px 12px;}
    .pdc-out .pdc-row .k{min-width:0;}
    .pdc-out .pdc-row .v{min-width:0;max-width:100%;overflow-wrap:anywhere;}
    .pdc-res-top{display:block;margin-bottom:10px;}
    .pdc-draw .val{font-size:2.1rem;overflow-wrap:anywhere;}
    .pdc-stats{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:8px;margin-top:14px;width:100%;}
    .pdc-stat{min-width:0;padding:10px;overflow-wrap:anywhere;}
    .pdc-stat:last-child:nth-child(odd){grid-column:1 / -1;}
    .pdc-syr{overflow-x:auto;overscroll-behavior-inline:contain;padding:4px 0 10px;scrollbar-width:thin;}
    .pdc-syr svg{min-width:500px;}
    .pdc-syr:focus-visible{outline:2px solid var(--pc);outline-offset:3px;border-radius:6px;}
    .pdc-tipbox{max-width:calc(100vw - 48px);}
    .pdc-res-foot{justify-content:stretch;}
    .pdc-copy{justify-content:center;width:100%;}
    .pdc-foot-links{display:grid;grid-template-columns:1fr;}
    .pdc-foot-links a{justify-content:center;}
  }